If and when a photograph is taken of US Vice-President JD Vance standing next to Iran's Parliamentary Speaker Mohammad Bagher Ghalibaf in Islamabad this weekend, it will make history.


That moment would mark the highest-level face-to-face talks between the Islamic Republic of Iran and the United States of America since the 1979 Islamic Revolution shattered their strong strategic bond and cast a long shadow which still darkens relations to this day.


The two men may not smile. They may not even shake hands. It would not make this troubled relationship any easier or less hostile. But it would send a signal that both sides want to try to end a war sending shocks worldwide, avoid an even riskier escalation, and turn to diplomacy to do a deal.


There's zero chance though of US President Donald Trump's optimistic prediction of a peace deal within this shaky two-week ceasefire - its terms were contested and broken since the moment it was announced earlier this week.


Even until the eleventh hour, Iranians kept everyone guessing over whether they would still show up while Israel was insisting there would be no ceasefire in Lebanon.


If serious and sustained talks make a start, it would also mark the most significant push since Trump pulled out of the previous landmark nuclear deal in 2018. Those talks, in rounds stretching over nearly 18 months of breakthroughs and breakdowns, were the last high-level meetings between then-US Secretary of State John Kerry and Iran's then-Foreign Minister Mohammad Javad Zarif.


Efforts since then, including during US President Joe Biden's term, made little headway.


Now, as high stakes surround the talks, Iran's reluctance and past experiences loom large. The gaps between the two sides remain very wide, with distrust running deep due to previous hostile interactions and recent military escalations.


As this pivotal moment unfolds, the deeply intertwined histories and recent climates of both Washington and Tehran play a crucial role in determining whether this engagement will foster progress or see repeated failures.