At least five people have been killed in Russian strikes across Ukraine, after a massive overnight aerial bombardment targeted several regions across the country.

A 61-year-old woman was killed when a drone hit an electric train in Kharkiv early on Tuesday, authorities said, while other deaths were reported in Zaporizhzhia, Kherson and Poltava.

Officials said the attacks were among the worst in ten days, and came hours after Ukrainian President Volodymyr Zelensky had warned of a forthcoming massive strike in his nightly address.

Russian strikes targeting energy infrastructure also disconnected Moldova's key power link with Europe, President Maia Sandu said, warning the situation remained fragile.

Sirens wailed across Ukraine on Monday night as Russia launched a barrage of missiles and drones at the country. Seven ballistic missiles, 23 cruise missiles, four air-launched guided missiles and 392 drones were used in the attack, the Ukrainian Air Force said in a statement on Telegram.

Air defense units intercepted 25 missiles and 365 drones, it added.

In a post on X on Tuesday, Zelensky said: These numbers clearly show that more protection is needed to save lives from Russian strikes. It is important to continue supporting Ukraine. Attacks of this scale have been occurring roughly once a week or every ten days in recent months, and there had been mounting fears in the past few days that another wave of strikes was imminent.

This time the attack focused on cities other than the capital, Kyiv. Damage was reported in eleven regions, Zelensky said. Among the worst affected was the south-eastern city of Zaporizhzhia, which was struck by six drones followed by six ballistic missiles. One person was killed and nine injured after a residential high-rise building was hit, local authorities said.

Local resident Dymtro Zaiets told Reuters news agency that his family was woken by a very loud explosion. We quickly gathered our things and ran downstairs, everything was on fire on our floor, he said. There was smoke, and we took our three-month-old child and ran quickly to the underground shelter. My car is destroyed. All our windows were blown out.

Elsewhere, at least two people were killed and 12 injured when strikes hit residential buildings and a hotel in the north-eastern Poltava region, governor Vitaliy Dyakivnych said on Telegram.

In Kherson, a civilian was killed when his house came under Russian shelling, the head of the city's military administration, Yaroslav Shanko, said.

Moldova's government condemned the strike on energy infrastructure in the Odesa region, which led to the disconnection of the Isaccea-Vulcanesti power line, used by Moldova to import electricity from neighbouring Romania. Alternative routes are in place, but the situation remains fragile, President Sandu wrote on X. Russia alone bears responsibility.

Moscow's overnight attack took place as the pace of the Russian advance in eastern Ukraine has slowed down significantly, with Ukrainian forces reporting minor counteroffensives in some areas.

Russia's defence ministry said its air defences had intercepted 55 Ukrainian fixed-wing unmanned aerial vehicles over various regions overnight.

Zelensky has previously warned that Russia will attempt to exploit the war in the Middle East to cause even greater destruction in Ukraine. Air-defense systems critical to Ukraine's ability to defend itself against Russian missile attacks are being rapidly expended in the US-Israel war with Iran.

Ukrainian and US officials held talks over the weekend over how to end Russia's full-scale invasion of Ukraine - the first such negotiations since the US and Israel launched strikes on Iran last month. Following talks on Sunday, Zelensky said it was clear that US attention was focused on Iran, but that this war of Russia against Ukraine must also be brought to an end.