James D. Watson, whose co-discovery of the double helix structure of DNA in 1953 illuminated the path for significant advancements in genetics, medicine, and forensic science, has passed away at the age of 97.

The landmark discovery made when Watson was just 24 years old, together with Francis Crick and Maurice Wilkins, led to the 1962 Nobel Prize in Physiology or Medicine and shaped understanding of genetic inheritance and cellular replication. His breakthrough not only defined a critical aspect of modern biology but also inspired countless innovations in areas from medical research to genealogy.

Despite his profound scientific contributions, Watson faced mounting criticism in his later years for controversial remarks regarding race and intelligence. His comments sparked a wave of professional backlash, resulting in his suspension from Cold Spring Harbor Laboratory and a tarnished public image.

Born on April 6, 1928, in Chicago, Watson often noted that his initial interest in genetics was piqued by reading about the essence of life. His passion led him to collaborate with Crick at Cambridge University, culminating in their production of a model that represented the DNA molecule as a double helix — a structure resembling a twisting ladder that would become a universal symbol of scientific inquiry.

In addition to winning the Nobel Prize, Watson played a pivotal role in the Human Genome Project, shaping policy in genetics research and advocating for ethical considerations throughout its scope. The completion of a working draft of the human genome in 2000 marked a historic milestone in biological research.

Watson died in hospice care after a brief illness. His son, Duncan, remarked on his father's enduring commitment to supporting those affected by diseases, emphasizing that Watson's initial motivation for pursuing genetic research stemmed from personal experience with illness in his family.

Nonetheless, the controversies surrounding his views, particularly his comments on intelligence and race, have sparked discussions about the intersection of science and social ethics. Even as he faced censure, Watson remained unapologetic about his beliefs, signifying a complicated legacy that juxtaposes groundbreaking scientific achievement with public controversies.

Reflecting on his career, Watson once remarked, There was no way we could have foreseen the explosive impact of the double helix on science and society. For better or worse, his work undoubtedly reshaped the landscape of modern science and continues to influence discussions about genetics today.