In detailing the justification for sanctions, the State Department accused the Palestinian leadership of trying to "internationalize" their conflict with Israel and supporting acts of violence and terrorism. In reaction, Palestinian representatives labeled the sanctions as retribution for their diplomatic successes, which they argue are aimed at achieving statehood and ending occupation.

The travel restrictions, which primarily affect the already intricate visa process for PA and PLO officials, are viewed in the context of the US's shifting role in Middle Eastern diplomacy—especially following a UN conference that criticized Israel’s actions during the ongoing Gaza conflict.

Current Palestinian political leaders maintain that the sanctions unjustly target those advocating for their people, while Israel has welcomed the US restrictions as a necessary stance against perceived terrorism. The complexities of these diplomatic relations continue to evolve amidst a backdrop of historical grievances, ongoing conflict, and a quest for statehood recognition within the global community.

As international recognition of Palestine grows, the US's role and strategies appear to be increasingly at odds with those of its allies, reflecting a significant shift in the geopolitical landscape of the region.